Lizzy Caplan

Biography

Elizabeth Anne Caplan (born June 30, 1982) is an American actress. Her performances as Virginia E. Johnson in the Showtime series Masters of Sex (2013–2016) and as Libby Epstein in FX on Hulu's Fleishman Is in Trouble (2022) have earned her nominations at the Primetime Emmy Awards. Her first acting role was on the television series Freaks and Geeks (1999–2000). Since then, she had series-regular roles in several television series including Related (2005–2006), Party Down (2009–2010; 2023), Das Boot (2018), Castle Rock (2019), Truth Be Told (2019), Fatal Attraction (2023), and Zero Day (2025). Caplan's film breakthrough came with her role as Janis Ian in Mean Girls (2004). Her other film appearances include My Best Friend's Girl (2008) Cloverfield (2008), Hot Tub Time Machine, 127 Hours (both 2010), Save the Date, Bachelorette (both 2012), The Interview (2014), Now You See Me 2, Allied (both 2016), and Cobweb (2023). Description above from the Wikipedia article Lizzy Caplan, licensed under CC-BY-SA, full list of contributors on Wikipedia.

Most Known For

The Simpsons

as Virginia Johnson (voice)

Family Guy

as Woman Arguing With Quagmire (voice)

Smallville

as Tina Greer

Watch What Happens Live with Andy Cohen

as Self - Guest

The Tonight Show Starring Jimmy Fallon

as Self

American Dad!

as Debbie (voice)

Late Night with Seth Meyers

as Self

Now You See Me: Now You Don't

as Lula

Conan

as Self

The View

as Self

New Girl

as Julia Cleary

True Blood

as Amy

Jimmy Kimmel Live!

as Self

Jimmy Kimmel Live!

as Self - Guest

Freaks and Geeks

as Sara

Childrens Hospital

as Casey Klein

Childrens Hospital

as Harmony

Castle Rock

as Annie Wilkes

The Last Leg

as Self

Inside Job

as Reagan Ridley (voice)